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| Effects of acupuncture at Fengchi (GB20) on voxel-mirrored homotopic connectivity in patients with posterior circulation ischemic vertigo |
| Hits 720 Download times 450 Received:August 12, 2022 |
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| DOI
10.11656/j.issn.1673-9043.2022.06.04 |
| Key Words
Fengchi;posterior circulation ischemic vertigo;voxel-mirrored homotopic connectivity;Resting state functional MRI |
| Author Name | Affiliation | E-mail | | YUAN Xiaojia | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | XU Yu | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | LI Xiaozhen | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | CHEN Zhengguang | Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | guangchenn999@sina.com |
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| Abstract
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| [Objective] To explore the alterations in interhemispheric functional connectivity in patients with posterior circulation ischemic vertigo using resting-state functional magnetic resonance imaging (rs-fMRI) with voxel-mirrored homotopic connectivity (VMHC) algorithm,to study the effective mechanisms of Fengchi (GB20) in dealing with posterior circulation ischemic vertigo. [Methods] Twenty patients with posterior circulation ischemic vertigo and 12 healthy controls were enrolled,the patients wereto receive acupuncture at Fengchi (GB20) and rs- fMRI scans before and after the acupuncture. The healthy controls were preformed rs-fMRI scan only once. Dizziness Handicap Inventory scores(DHI) were used to evaluate the severity of vertigo in all patients. After the imaging preprocessing,VMHC values were obtained by Data Processing & Analysis for (Resting-State) Brain Imaging (DPABI) software. T test was used to compare VMHC in patients before and after needling Fengchi (GB20),and with healthy controls. Correlations were performed between VMHC values and DHI. [Results] Compared with VMHC maps before needling Fengchi (GB20),increased VMHC values were shown in inferior temporal gyrus,superior frontal gyrus and precuneus. There was no significant correlation between VMHC and DHI scores. No alteration of VMHC was found between PCIV patients and healthy controls. [Conclusion] The voxel-mirrored homotopic connectivity is different in areas connected with vestibular functions before and after needling Fengchi (GB20),indicating that may be one of the effective mechanisms for the treatment of vertigo in posterior circulation ischemic patients. |
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