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| Evaluation of the efficacy Wenxin Granule in the treatment of ventricular premature beats based on Meta-analysis |
| Hits 539 Download times 879 Received:October 21, 2022 |
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| DOI
10.11656/j.issn.1673-9043.2023.02.11 |
| Key Words
Wenxin Granule;Meta analysis;economic evaluation;clinical efficacy |
| Author Name | Affiliation | E-mail | | MA Luyao | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Meina | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | SUN Xiao | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LI Mingxiu | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Xiangyu | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Huiyi | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | REN Ming | Baokang Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | renming2008@126.com |
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| Abstract
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| [Objective] Based on Meta-analysis of the effectiveness, safety, and economy of Wenxin Granules in the treatment of ventricular premature beats.[Methods] Using "Wenxin granule" "Wenxin" as search terms, a computer search of China Knowledge Network (CNKI), Wanfang database (WF), VIP database (VIP), Pubmed and The Cochrane Library and other databases (January 2000 to August 2020), and manually search-related journals and conference papers to screen randomized controlled trials literature of Wenxin granules in the treatment of ventricular premature beats. Use RevMan 5.3 software to carry out Meta-analysis, and carry out an economic evaluation in combination with cost-effectiveness.[Results] The 10 articles were included, with a total of 995 patients. Meta-analysis results show that compared with Xinlvping, Wenxin Granules treatment of ventricular premature beats improves the clinical efficacy, improves the efficacy of dynamic electrocardiogram and electrocardiogram, and reduces the incidence of adverse reactions. Pharmacoeconomics shows that Wenxin Granules have cost-effective advantages in treating ventricular premature beats. Single-factor sensitivity analysis confirmed the stability of the results.[Conclusion] Wenxin Granules has good efficacy, safety, and economy in the treatment of ventricular premature beats, but a large number of high-quality samples are required for randomized controlled trials and verification. |
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