|
| Research progress in the gut microbiota-metabolic network of chronic kidney disease and application of traditional Chinese medicine |
| Hits 586 Download times 356 Received:February 05, 2023 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2023.03.18 |
| Key Words
chronic kidney disease;renal-intestinal axis;gut microbiota;metabolite;treatment and medication |
| Author Name | Affiliation | E-mail | | LI Jiaqi | Nephrology Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | WANG Jingyi | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XING Haitao | Nephrology Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | YANG Hongtao | Nephrology Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | tjtcmht@126.com |
|
| Abstract
|
| In recent years,the gut microbiota and derived metabolites of chronic kidney disease(CKD) have been widely studied,and traditional Chinese medicine(TCM) treatment methods based on this as an intervention target have great application value in delaying the development of CKD. In this paper,we firstly introduced the current status of intestinal microecology in CKD. Then,we discussed the pathogenic principles of gut microbiota and derived metabolites network in CKD based on the renal-intestinal axis. Finally,based on the treatment concept under the guidance of classical Chinese medicine theory and modern pharmacological research,the specific treatment and medication of TCM intervention in the gut microbiota-metabolic network of CKD were summarized,aiming to further clarify the application value of TCM intervention in CKD by targeting the gut microbiota and their metabolites. |
|
|
|
|
|
