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| Analysis of the treatment and prescription regularity of vascular dementia |
| Hits 397 Download times 887 Received:March 05, 2023 |
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| DOI
10.11656/j.issn.1673-9043.2023.04.09 |
| Key Words
vascular dementia;traditional Chinese medicine;treatment;medication regularity |
| Author Name | Affiliation | E-mail | | CHEN Xueyan | The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
Department of Encephalopathy and Psychiatry, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China | | | ZHANG Jie | Guangzhou Traditional Chinese Medicine Hospital Affiliated to Guangzhou University of Chinese Medicine, Guangzhou 510130, China | | | MO Jiaxin | The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | QIN Xiude | The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
Department of Encephalopathy and Psychiatry, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China | qinxiude@foxmail.com | | HUANG Mengni | The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510006, China
Department of Encephalopathy and Psychiatry, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, China | |
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| Abstract
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| [Objective] To analyze the treatment and rule of clinical prescription of traditional Chinese medicine(TCM) for vascular dementia.[Methods] We searched CNKI,VIP and Wanfang for the literature related to TCM for vascular dementia,and conducted strictly literature screening and data extraction accorrding to inlusion and exclusion criteria. Then,after constructing a database of prescriptions for vascular dementia,we used the TCM Heritage Computing Platform V3.0 and SPSS clementine12.0 for frequency statistics,association rule analysis and clustering analysis.[Results] Based on the statistical analysis of 276 prescriptions,the herbs with a frequency of over one hundred were Shi Calamus,Chuanxiong,Dan Shen,Huang qi,Yuan Zhi and Shu Di Huang,and the treatment is based on tonifying the kidneys,invigorating blood,resolving blood stasis,resolving phlegm,benefiting qi and opening the orifices. The results of the association rule analysis showed that a total of 18 high-frequency drug pairs and 36 drug-syndromes pairs were obtained,and the cluster analysis yielded four sets of combinations.[Conclusion] The basic treatment of vascular dementia in TCM is to tonify deficiency,invigorate blood and resolve phlegm,with emphasis on the co-management of deficiency,phlegm and stasis. |
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