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| Research progress in animal models of airway hyperreactive disease |
| Hits 398 Download times 477 Received:June 07, 2023 |
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| DOI
10.11656/j.issn.1673-9043.2023.05.16 |
| Key Words
airway hyperreactivity;asthma;chronic obstructive pulmonary disease;gastroesophageal reflux;COVID-19;animal model |
| Author Name | Affiliation | E-mail | | ZHANG Wenjing | Institute of Chinese Medicine, Tianjin University of Chinese Medicine, Tianjin 301617, China | | | DAI Xiangdong | Institute of Chinese Medicine, Tianjin University of Chinese Medicine, Tianjin 301617, China | | | LIU Shuai | Institute of Chinese Medicine, Tianjin University of Chinese Medicine, Tianjin 301617, China | | | ZHANG Han | Institute of Chinese Medicine, Tianjin University of Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin 301617, China | zhanghan0023@126.com | | LI Lin | Institute of Chinese Medicine, Tianjin University of Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-Based Chinese Medicine, Tianjin 301617, China | lilintcm@126.com |
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| Abstract
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| Airway hyperreactivity(AHR),as a common clinical disease characteristic,is mainly seen in bronchial asthma,chronic obstructive pulmonary disease,novel coronavirus disease,gastroesophageal reflux and other diseases. The increasing incidence of AHR directly threatens human health. To study the etiology and pathogenesis of these diseases,and to develop and evaluate new drugs,mature and reliable experimental animal models are needed as tools. In this paper,the modeling methods of the above four kinds of animal models with airway hyperreactivity are discussed,which can provide reference for the basic research of these diseases. |
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