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Overview of research on Suoquan Pill in the treatment of infantile enuresis baseed on modulation of detrusor muscle
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DOI   10.11656/j.issn.1673-9043.2023.05.19
Key Words   infantile enuresis;Suoquan Pill;detrusor muscle;review
Author NameAffiliationE-mail
NIU Jing Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China  
ZHOU Xue Department of Respiratory Medicine, Children's Hospital of Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou 450000, China  
CHEN Tuanying Department of Pediatrics, Henan Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China yifan96606@126.com 
Abstract
    Infantile enuresis is one of the most commom clinical disease,and its prevalence has gradually increased in recent years. Infantile enuresis may not only affect the neurological and mental development of children,but also adversely affect the physical and mental growth of children. Suoquan Pill is one of the most effective prescriptions in the clinical treatment of pediatric enuresis. By reviewing the relevant literature in recent years,this paper briefly explained that Suoquan Pill maintained the balance of β3-adrenergic receptor(β3-AR) and M3 muscarinic acetylcholine receptor(M3 receptor),regulating the abnormal pelvic nerve discharge,and regulating the ion channel to stabilize the detrusor muscle to warm the kidney qi,shrink urine and stop urination,which provides some objective basis for the clinical efficacy mechanism of Suoquan pill.

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