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| Literature analysis of 57 cases of adverse event/adverse drug reaction caused by Xiyanping Injection |
| Hits 448 Download times 373 Received:August 31, 2023 |
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| DOI
10.11656/j.issn.1673-9043.2024.01.06 |
| Key Words
Xiyanping Injection;adverse drug reaction;literature analysis |
| Author Name | Affiliation | E-mail | | DU Xuechen | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | JIN Xinyao | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Chunyang | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | CAO Lujia | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHENG Wenke | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Haihe Laboratory of Modern Chinese Medicine, Tianjin 301617, China | zhengwk2020@tjutcm.edu.cn |
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| Abstract
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| [Objective] Inspect the regularity of adverse drug reaction to Xiyanping Injection based on clinical adverse reactions reports and provide reference for clinical rational medication. [Methods] Adopts literature analysis method and searches for adverse reaction reports of Xiyanping Injection in CNKI, Wanfang, SinoMed and other databases. Analyzes the relevant factors in the studies and summarizes the occurrence regularity of adverse reactions. [Results] Total 52 related literatures are studied, including 57 adverse event/adverse drug reaction cases. The analysis results demonstrate that among Xiyanping Injection-related adverse event/adverse drug reactions medication beyond instructions cases are rarely observed. The relationship between the occurrence of adverse event/adverse drug reaction and gender or allergic history is not yet found. Adverse event/adverse drug reaction mainly occurred in the <10 years old age group, and most of the patients were in the early stage of respiratory infections. Adverse event/adverse drug reaction usually occurs in the first 30 minutes after injection. The main type of adverse event/adverse drug reaction is allergic reaction. After effective clinical treatment, adverse drug reaction has a favorable prognosis, no sequelae or liver and kidney damage. [Conclusion] There are many possible factors that may cause Xiyanping adverse event/adverse drug reaction, and the main clinical manifestation is allergic reaction. Most of the symptoms develop very fast, but after timely treatment, the prognosis is usually good and there is no liver and kidney damage. |
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