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| Systematic review and meta-analysis of the effect of Baduanjin on pre-diabetic patients |
| Hits 197 Download times 181 Received:November 10, 2023 |
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| DOI
10.11656/j.issn.1673-9043.2024.03.07 |
| Key Words
pre-diabetes;Baduanjin;systematic review;meta analysis;randomized controlled trial |
| Author Name | Affiliation | E-mail | | SUN Xin | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Department of Internal Medicine, Tianjin Hexi District traditional Chinese Medicine Hospital, Tianjin 300210, China | | | ZHANG Chunmei | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Dawei | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAI Jingbo | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | HAN Meijia | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | hanmeijia415@163.com | | ZHANG Jianfeng | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Xuanchen | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | WANG Huaijie | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | |
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| Abstract
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| [Objective] To systematically evaluate the effect of Baduanjin exercise on patients with pre-diabetes （PDM）. [Methods] Computer retrieval of PubMed，Embase，CochraneLibrary，CBM，CNKI，WanFang，and VIP databases was conducted to collect randomized controlled trials（RCTs） on the impact of Baduanjin exercise on PDM patients. The retrieval time was from the database establishment until September 2022. Two researchers independently screened the literature，extracted the data，and evaluated the risk of bias included in the study. Then，a metaanalysis was conducted using Revman 5.4.1 software. [Results] A total of 11 RCT studies were included，including 665 patients. Meta analysis results showed that：1）In terms of glucose metabolism，compared with the control group， the Baduanjin exercise can reduce fasting blood glucose [MD=-0.46，95%CI （-0.60，-0.31），P＜0.01]，glycated hemoglobin [MD=-0.46，95%CI （-0.82，-0.10），P=0.01]，fasting insulin [MD=-1.32，95%CI （-2.06，-0.57），P= 0.0005]，and insulin resistance index [MD=-0.60，95%CI （-0.87，-0.33），P＜0.01]. ２）In terms of body improvement，compared with the control group，Baduanjin exercise can reduce body mass index [MD=-1.04，95%CI（-1.28， -0.80），P＜0.01]；The results of subgroup analysis of waist to hip ratio indicators indicate that compared with the conventional treatment group，the Baduanjin exercise can reduce the waist to hip ratio of PDM patients [MD=-0.03， 95%CI（-0.04，-0.02），P＜0.01]. Compared with the control group of walking or walking，there is no statistically significant difference in the waist to hip ratio between the two groups [MD=-0.01，95%CI（-0.03，-0.01），P=0.43]. 3）In terms of improving quality of life，compared with the control group，Baduanjin exercise can improve physiological health scores [MD=8.68，95%CI（5.06，12.29），P＜0.01] and psychological health scores [MD=6.95，95%CI（4.86， 9.04），P＜0.01]. [Conclusion] Current evidence shows that Baduanjin exercise can improve fasting blood glucose， glycated hemoglobin，fasting insulin，and insulin resistance index in PDM patients，reduce body mass index and waist to hip ratio，improve physical and mental health scores，and have good safety. It has good promotion and application value for PDM patients. However，due to the limitations of the number and quality of included studies，the above conclusions still need to be further validated through more high-quality randomized controlled clinical trials. |
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