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| Recent advances in antioxidant activity of Polydatin |
| Hits 234 Download times 392 Received:November 08, 2023 |
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| DOI
10.11656/j.issn.1673-9043.2024.04.08 |
| Key Words
Polygonum cuspidatum;Polydatin;antioxidant;application;mechanism of action |
| Author Name | Affiliation | E-mail | | JIN Yajing | School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China | | | DANG Lingling | School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China | | | CHEN Xiyu | School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China | | | ZHANG Tianyuan | School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China | | | WANG Yu | School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China | wangyu@tjutcm.edu.cn | | SHAO Rui | State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | rizycarrot@tjutcm.edu.cn |
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| Abstract
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| Polydatin,the monomeric component extracted from the dried rhizomes of Chinese herb Polygonum cuspidatum,is a glucoside derivative of resveratrol. Modern pharmacologic studies demonstrated that Polydatin plays essential roles in numerous important biological processes,including oxidative stress,inflammation,apoptosis and so on. Polydatin has received much attention due to its higher antioxidant activity and enhanced bioavailability,when compared with resveratrol. Recent studies have found that Polydatin can be applied in the treat of a variety of oxidative stress-related diseases,including neurodegenerative diseases,diabetes,cardiovascular diseases and so on. In this review,we systematically discussed the antioxidant effects of Polydatin in a wide variety of common diseases. We expect to provide reference for future research on the potential development and utilization of Polydatin. |
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