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Research progress of classical prescriptions of Xiebai San and predictive analysis on its quality marker
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DOI   10.11656/j.issn.1673-9043.2024.04.09
Key Words   Xiebai San;quality marker;quality control
Author NameAffiliationE-mail
YAO Chunxu Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co. Ltd., Tianjin 300380, China 
 
ZHANG Jingze Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co. Ltd., Tianjin 300380, China 
 
LIU Dailin Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Modern Innovation Chinese Medicine Technology Co. Ltd., Tianjin 300380, China 
dailinlch@163.com 
Abstract
    Xiebai San is from Key to Therapeutics of Pediatric Disease written by QIAN Yi in the Song Dynasty. It has the efficacy of clearing heat,moistening the lung,calm panting and suppressing cough,clinically used for preventing pyretic pulmonary disease. In this study,it provides an overview of the chemical composition and pharmacological effects of Xiebai San. Additionally,we applied the "five principles" of traditional Chinese medicine to predict its quality marker(Q-Marker). According to findings,mulberroside A,kuwanon G,morusin,kukoamine B,kukoamine A,liquiritin and glycyrrhizic acid could be served as the Q-Marker of Xiebai San. These results provide a valuable reference for enhancing the quality evaluation and control system of Xiebai San.

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