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| Research progress of Panax notoginseng saponins and its preparation in the treatment of diabetic retinopathy |
| Hits 217 Download times 255 Received:January 11, 2024 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1673-9043.2024.04.10 |
| Key Words
diabetic retinopathy;traditional Chinese medicine;Panax notoginseng saponins;dosage form |
| Author Name | Affiliation | E-mail | | YU Changxiang | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHONG Yuhong | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XING Bin | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | JIA Xintao | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Ying | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Qingqing | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Zhidong | State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Engineering Research Center of Modern Chinese Medicine Discovery and Preparation Technique, Ministry of Education, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | lonerliuzd@163.com |
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| Abstract
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| Diabetic retinopathy(DR) is a common complication of diabetes and the main cause of blindness in diabetics,which seriously affects the quality of life of diabetics. At present,the main clinical treatment methods of DR include surgical treatment,laser treatment and drug treatment. Among them,drug therapy can intervene in multiple aspects of disease development and reduce complications related to laser treatment and surgical treatment. However,due to the particularity of the eye structure,the bioavailability of drugs is low,and there is an urgent need to seek and develop drugs with good efficacy and low toxic side effects and suitable dosage forms. Traditional Chinese medicine has the advantages of long history,wide origin,multi-target synergy,etc.,and has unique advantages in the treatment of DR. Panax notoginseng saponins are the main active ingredient group extracted from Panax notoginseng,which has been confirmed to have the effect of treating DR. In this paper,the mechanism of Panax notoginseng saponins in the treatment of DR and the dosage forms of Panax notoginseng in the clinical application was analyzed and summarized,which broadens the horizon of the development of pharmaceutical dosage forms of Panax notoginseng saponins. |
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