Home      About this journal      Authors      Referees      Editors      Readers      Archive      Contact us
Research progress on pharmacological effects of Sini San and predictive analysis of its quality markers
Hits 200  Download times 490  Received:October 29, 2023  
View Full Text  View/Add Comment  Download reader
DOI   10.11656/j.issn.1673-9043.2024.05.12
Key Words   Sini San;pharmacological effect;quality marker;quality control
Author NameAffiliationE-mail
ZHANG Zhuo College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
ZHANG Yang College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
XIE Jingyi College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
YIN Jiaxin College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
BIE Songtao College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
Modern Traditional Chinese Medicine Haihe Laboratory, Tianjin 301617, China 		 
SONG Xinbo College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
Modern Traditional Chinese Medicine Haihe Laboratory, Tianjin 301617, China 		 
YU Heshui College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
Modern Traditional Chinese Medicine Haihe Laboratory, Tianjin 301617, China 		hs_yu08@163.com 
LI Zheng College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
State Key Laboratory of Component-based Chinese Medicine, Tianjin 301617, China
Modern Traditional Chinese Medicine Haihe Laboratory, Tianjin 301617, China 		 
Abstract
    Sini San is composed of Prepared glycyrrhiza，Radix bupleuri，Radix paeoniae alba，Citrus aurantium L，Aurantii fructus immaturus. It has the effect of removing pathogenic factors and relieving depression，soothing the liver and regulating the spleen. Modern pharmacological studies have shown that the drug has anti-depression，liver protection，treatment of functional dyspepsia，improvement of arteriosclerosis，sedative-hypnotic and anti-ulcer effects. On the basis of summarizing the research progress of pharmacological effects of Sini San，the quality marker of Sini San was predicted and analyzed according to the “five principles” of Q-marker in traditional Chinese medicine. The results suggested that liquiritin，liquiritigenin，glycyrrhetinic acid，glycyrrhizic acid，kaempferol，quercetin，naringin，saikosaponin a，saikosaponin d，paeoniflorin，albiflorin，hesperidin，neohesperidin，synephrine could be used as quality markers of Sini San，in order to provide reference for the quality control of Sini San.

You are the 1624071 visitor.

Copyright @ 2007
Address:   Postcode:
Tel:  Fax:  E-mail:
Beijing E-Tiller Co., Ltd.