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| Effects of Niaoduqing Granule on glucose metabolism and inflammatory reaction in diabetes nephropathy |
| Hits 145 Download times 193 Received:April 26, 2024 |
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| DOI
10.11656/j.issn.1673-9043.2024.07.05 |
| Key Words
Niaoduqing Granule;diabetes nephropathy;sugar metabolism;inflammatory reaction |
| Author Name | Affiliation | | YANG Yang | Department Eleven of Endocrinology, Shijiazhuang Second Hospital, Shijiazhuang 050031, China |
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| Abstract
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| [Objective] To study the effect of Niaoduqing Granule on glucose metabolism and inflammatory reaction in diabetes nephropathy. [Methods] Retrospectively select 57 patients with diabetes nephropathy who received conventional treatment from July 2022 to September 2023 as the control group，and select 57 patients with diabetes nephropathy who received conventional treatment plus auxiliary treatment of Niaoduqing Granule at the same time as the study group. Compare the glucose metabolism indicators，inflammatory factor indicators，and renal function indicators before and after treatment between two groups，and analyze the correlation between glucose metabolism indicators，inflammatory factor indicators，and renal function indicators after treatment. Record liver function indicators and adverse drug reactions during treatment. [Results] There was no statistically significant difference in various indicators before treatmenｔ（P＞0.05）. After treatment，the FPG，2 hPG，HbA1c，hs-CRP，IL-6，TNF-α，Scr，BUN，and ACR of the study group were lower than those of the control group（P＜0.05）. The glucose metabolism indicatoｒs（FPG，2 hPG，HbA1c) and inflammatory factor indicatoｒs（hs-CRP，ＩL-6，TNF-α） ｏｆ 114 patients after treatment were positively correlated with Scr，BUN，and ACR after treatment（P＜0.05）. There was no statistically significant differencｅ（P＞0.05） in ALT and AST before and after treatment in both groups，and no adverse reactions occurred. [Conclusion] The auxiliary treatment of Niaoduqing Granule for patients with diabetes nephropathy can effectively improve the indicators of glucose metabolism，reduce inflammatory reaction，help improve the renal function of patients，and has good safety. |
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