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Bibliometrics-based analysis of progress of traditional Chinese medicine compound in the treatment of chemotherapy-induced nausea and vomiting
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DOI   10.11656/j.issn.1673-9043.2024.11.08
Key Words   traditional Chinese medicine;chemotherapy-induced nausea and vomiting;chemotherapy;bibliometrics;malignment tumor
Author NameAffiliationE-mail
ZHU Rui Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LI Na Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
REN Xiaoliang School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China renxiaoliang@tjutcm.edu.cn 
WANG Meng Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China wangmeng@tjutcm.edu.cn 
Abstract
    [Objective] To summarize the high-frequency use of traditional Chinese medicine(TCM) compounds in the treatment of chemotherapy-induced nausea and vomiting(CINV), analyze their composition and clinical use frequency, and summarize the research status and development prospects of TCM in the treatment of CINV. [Methods] China National Knowledge Infrastructure(CNKI) was searched for literature on the treatment of CINV in the past decade(2010-2021). Bibliometrics was used to analyze the characteristics of the effects and preparation development of the top 12 TCM compounds(non-traditional decoctions) in the treatment of CINV, and CiteSpace was used to analyze the co-occurrence analysis of keywords, keyword clustering and keyword timeline. [Results] A total of 185 related literature articles were screened, among which the traditional Chinese medicine compound formula and single flavor Chinese medicine with the highest frequency of treatment of CINV were Xuanfu Dai Ochre Tang and Tangerine Peel, respectively. The common clinical preparation forms of various TCM compounds are granules and formula granules. The existing research on the treatment of CINV is complex, and the main research hotspots focus on the types of trials, clinical symptoms, key indicators of mechanism research, and types of preparations. [Conclusion] The existing TCM clinical treatment of CINV drugs are mainly derived from Jing Fang, and are currently in the main stage of preparation development and mechanism research, but the current form of preparation is single, and the research and development of modern TCM preparation products is still urgent.

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