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| Comparative study on syndrome of diabetes nephropathy in micro proteinuria stage and clinical proteinuria stage based on data mining technology |
| Hits 78 Download times 22 Received:September 15, 2024 |
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| DOI
10.11656/j.issn.1673-9043.2024.11.09 |
| Key Words
diabetic nephropathy;data mining;TCM syndrome;microalbuminuria period;clinical proteinuria period |
| Author Name | Affiliation | E-mail | | XU Yanchao | Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China | | | ZHENG Shuqin | The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110847, China | qxjzsq@sina.com |
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| Abstract
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| [Objective] To analyze the related literature of diabetic nephropathy（DN）, and to compare the characteristics of Traditional Chinese Medicine（TCM） syndromes between microalbuminuria stage and clinical proteinuria stage by using data mining technology, so as to provide new ideas for clinical standardized staging treatment of DN. [Methods] The relevant literatures included in CNKI, Wanfang Data Knowledge Service Platform and VIP Chinese Science and Technology Periodical Database from January 1, 2014 to December 31, 2023 were retrieved, and the literatures that met the inclusion criteria were screened, and the syndromes and symptoms were extracted, the names were standardized and split. A database was established, and statistical software was used to perform frequency statistics and cluster analysis on the syndromes related to microalbuminuria and clinical proteinuria of DN. [Results] A total of 3 506 articles were retrieved and 79 articles were finally included. In terms of syndromes, qi and yin deficiency, blood stasis syndrome, spleen and kidney qi deficiency, damp heat syndrome, yindeficiency and dryness heat and damp turbidity syndrome are the most common in microalbuminuria period；qi and yin deficiency, blood stasis syndrome, spleen and kidney qi deficiency, yin andyang deficiency, damp-heat syndrome and phlegm-dampness syndrome are the most common clinical proteinuria.In terms of symptoms, the common symptoms of microalbuminuria are lassitude, thirst and polydipsia, dry mouth and dry throat, limb numbness, blurred vision, frequent nocturia, soreness and weakness of waist and knees, dizziness, insomnia and dreaminess, limb pain；the common symptoms of clinical proteinuria are lassitude, limb numbness, edema, blurred vision, soreness and weakness of waist and knees, dry mouth and throat, thirst and more drinking, dizziness, less gas and lazy words, and turbid urine. [Conclusion] With the progression of the disease, the clinical proteinuria period of DN compared with the microalbuminuria period, the types of syndromes are more complex and diverse, and the proportion of yang deficiency related syndromes is significantly increased. |
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