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| Clinical effect of modified formula of Zhujing Wan combined with traditional Chinese medicine fumigation in the treatment of dry eye syndrome |
| Hits 46 Download times 24 Received:July 20, 2024 |
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| DOI
10.11656/j.issn.1673-9043.2024.12.04 |
| Key Words
dry eye syndrome;artificial tears;modified formula for Zhujing Wan;Chinese herbal fumigation |
| Author Name | Affiliation | E-mail | | ZHAO Minghui | Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | QUAN Zhe | Internal Medicine Department, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | HUANG Ziyin | Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China | | | LI Juan | Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | LIU Rui | Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | LIU Jiali | Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China | | | SONG Yi | Department of Ophthalmology, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200071, China
Shanghai Hospital Traditional Chinese Medicine Preparation Industry Transformation Collaborative Innovation Center, Shanghai 201203, China | eseyes@163.com |
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| Abstract
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| [Objective] To analyze the clinical efficacy of using artificial tears combined with modified Zhujing Wan orally and traditional Chinese medicine(TCM) fumigation for the treatment of dry eye syndrome. [Methods] This study employed a retrospective research approach. Collect baseline data of 60 patients(120 eyes) with dry eye syndrome who visited our ophthalmology clinic from March 2022 to February 2024. According to different treatment methods,the patients were divided into a control group and a traditional Chinese and Western medicine treatment group. The control group was treated with sodium hyaluronate eye drops alone,while the traditional Chinese and Western medicine treatment group was treated with sodium hyaluronate eye drops in addition to the modified formula of Zhujing Wan orally,combined with TCM fumigation treatment. Each group had 30 cases(60 eyes). After 4 weeks of treatment,compare the dry eye related clinical indicators between the two groups of patients. [Results] After 4 weeks of treatment,the total effective rate of the control group was 76.7%,while the total effective rate of the traditional Chinese and Western medicine treatment group was 90.0%. There was a significant difference in the total effective rate between the two groups(P<0.05). Compared with before treatment,both groups of patients showed prolonged fluorescein stained tear film rupture time(FBUT),increased tear secretion test(SIT) values,and decreased corneal fluorescence staining scores,with significant statistical differences compared to before treatment(P<0.01 for both groups). Compared with the control group,the FBUT and SIT values increased more in the traditional Chinese and Western medicine treatment group,and the corneal fluorescence staining score decreased more significantly,with significant statistical differences(P<0.01). [Conclusion] The use of artificial tears combined with modified Zhujing Wan orally,combined with TCM fumigation,is effective,safe,and can effectively improve the clinical symptoms of dry eye syndrome in patients. |
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