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| Traditional Chinese medicine syndrome analysis of 499 cases of mild influenza A |
| Hits 8 Download times 1 Received:October 05, 2024 |
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| DOI
10.11656/j.issn.1673-9043.2025.02.04 |
| Key Words
influenza A;syndrome of traditional Chinese medicine;latent category analysis;logistic regression analysis |
| Author Name | Affiliation | E-mail | | ZHAO Jingmin | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | SU Rina | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Sihan | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHAO Qiliang | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | ZHANG Huiqi | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | DU Jinghui | National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | LIU Min | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | liumintcm@163.com | | SUN Hongyuan | Department of Infectious Diseases, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China
National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | | | SUN Xin | Tianjin People's Hospital, Tianjin 300120, China | | | LI Guiwei | National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China | |
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| Abstract
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| [Objective] To explore the Chinese medicine evidence for mild influenza A illness using latent class analysis.[Methods] Information on four consultations of patients with mild influenza A was collected,and SPSS 25.0 and Mplus 8.3 software were used to analyze the frequency of descriptive data,extract the items with greater relevance to mild influenza A by factor analysis,and then perform potential category analysis to summarize the main Chinese medicine symptoms,and perform logistic regression analysis on the factors that might affect the distribution of Chinese medicine symptoms.[Results] A total of 499 patients were included,and the frequency of symptoms,in descending order,were cough,muscle pain,fatigue,red throat,and severe headache,etc.. Twenty-two symptomatic items of high relevance to the mild symptoms of influenza A were extracted by factor analysis,and four types of traditional Chinese medicine symptom manifestation combinations were derived from the analysis of potential categories,namely,the wind-cool bundle of surface symptoms(25.1%),the wind-heat offending the wei and dampness symptoms(44.5%),the surface cold and internal heat symptoms(20%)(10.4%)[1]. Logistic regression analysis showed that with the wind-heat offending the guard and entrapping dampness syndrome as the reference,the likelihood of manifesting the wind-cold bundled surface syndrome for a disease duration of ≤ 1 day was 1.955 times higher than that of a disease duration of >2 days(OR=1.955,95%CI=1.024-3.732,P=0.042),and that the likelihood of manifesting the wind-cold bundled surface syndrome and the epidemiological-cold and internal-heat syndrome without the use of medication prior to the visit was higher than that of using antidotes prior to the visit,respectively were 0.267 times more likely(OR=0.267,95%CI=0.087-0.822,P=0.021) and 0.281 times more likely(OR=0.281,95%CI=0.081-0.975,P=0.046),respectively than those who had used antiviral medication prior to the consultation.[Conclusion] Most of the mild cases of influenza A were wind-heat against the guard and dampness syndrome,followed by wind-cold bundle surface syndrome,surface-cold and internal-heat syndrome,and wind-heat against the guard. The short course of disease is mainly due to exterior syndrome of wind-cold bundle,and the syndrome of wind-heat invading wei and dampness is the main one without antiviral drugs. |
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