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| Research progress of traditional Chinese medicine intervention in diabetic nephropathy based on fatty acid metabolic reprogramming |
| Hits 383 Download times 221 Received:January 12, 2025 |
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| DOI
10.11656/j.issn.1673-9043.2025.04.12 |
| Key Words
diabetic nephropathy;fatty acid metabolism;traditional Chinese medicine;research progress |
| Author Name | Affiliation | E-mail | | GU Mengtong | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | | | FANG Cheng | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | | | WANG Xu | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | | | YAN Li | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | | | XIANG Yujie | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | | | WU Xiuhong | College of Pharmacy, Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China | wxh8088@163.com |
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| Abstract
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| Diabetic nephropathy（DN） is one of the most common micro-vascular complications of diabetes. It is also the main risk factor of end-stage renal disease. In recent years，the research on the relationship between lipid metabolism and DN in the field of traditional Chinese medicine（TCM） has been increasing year by year. Fatty acid metabolism is an important link in lipid metabolism and is closely related to the occurrence and development of DN. The treatment of DN by TCM has a long history and good curative effect，and the mechanism of regulating fatty acid metabolism by TCM has been discovered and revealed. Therefore，this paper discusses the relationship between fatty acid metabolism disorders and DN，summarizes the TCM methods targeting fatty acid metabolism disorders to alleviate diabetic kidney disease，and provides references for further research on the relevant mechanism of DN fatty acid metabolism and searching for targeted intervention means，in order to provide a reference for the prevention and treatment of DN. |
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