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| Research progress review on ancient and modern clinical medication safety studies of Aconiti Lateralis Radix Praeparata |
| Hits 400 Download times 431 Received:February 18, 2025 |
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| DOI
10.11656/j.issn.1673-9043.2025.06.12 |
| Key Words
Aconiti Lateralis Radix Praeparata;Clinical application;Detoxification;Safety |
| Author Name | Affiliation | E-mail | | LI Shuangqing | Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | MAO Xinyu | Clinical Pharmacology Research Center, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | XING Yongfa | Clinical Pharmacology Research Center, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | | ZHANG Li | Clinical Pharmacology Research Center, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | tjgcp_zl@126.com | | WANG Baohe | Binhai New Area Hospital of Traditional Chinese Medicine, Fourth Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300450, China | |
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| Abstract
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| The safety of Aconiti Lateralis Radix Praeparata(Fuzi) has long been a focal and challenging issue in clinical practice. Historically, medical practitioners have held divergent perspectives on its toxicity, and its misuse often leads to severe adverse outcomes. This study investigates the safety concerns of Fuzi in clinical application through a multidimensional approach, encompassing ancient textual records, clinical practical experience, analysis of toxic components, and strategies for enhancing efficacy and reducing toxicity. By systematically examining the inherent risks and toxicological profile of Fuzi, this research provides a comprehensive and detailed evaluation of its clinical applicability. Through rigorous scientific methods, the paper establishes a reference framework to guide clinicians in the safe and rational use of Fuzi, aiming to mitigate risks associated with improper administration and ensure medication safety. |
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