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Exploring the mechanism of action of Jing points and Xuan points in treating diseases based on blood vessel spheroids
Hits 378  Download times 205  Received:March 03, 2025  
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DOI   10.11656/j.issn.1673-9043.2025.08.11
Key Words   vascular sphere;acupuncture;Jing point;Xuan point;cerebral blood flow;microcirculation disorder
Author NameAffiliationE-mail
WANG Jiangshan Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
LU Fengda Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
YAO Kaifang Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
XU Zhifang Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
School of Acupuncture & Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin 301617
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin 301617, China 
 
FAN Zezhi Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
DU Simin Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
WU Yongjian Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
REN Haiyan Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin 301617, China
Tianjin University of Traditional Chinese Medicine College of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Smart Traditional Chinese Medicine Industry College, Tianjin 301617, China 
rhyxiaotong@163.com 
GUO Yi Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
School of Acupuncture & Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin 301617
Tianjin Key Laboratory of Modern Chinese Medicine Theory of Innovation and Application, Tianjin 301617, China
Tianjin Smart Traditional Chinese Medicine Industry College, Tianjin 301617, China 
guoyi_168@163.com 
Abstract
    Modern research shows that the meridian and Xuan points are located at the ends of fingers and toes. These acupoints are not only the starting points of the twelve meridians,but also have direct connections with the arteriovenous anastomoses. At the same time,vascular spheroids are widely distributed in the distal areas of the fingers and feet,especially the nail bed of the thumb and the dermis layer below it. These vascular bulbs are mainly composed of arteriovenous anastomotic branches,and are therefore structurally and functionally related to Jing and Xuan points. Based on this,the glomus is considered to be a potential key target for stimulating Jing and Xuan points in acupuncture treatment. Further research shows that vascular spheroids play a crucial role in improving microcirculation disorders,regulating sympathetic nerves,and regulating immunity. These findings not only provide scientific basis for understanding the therapeutic mechanisms of Jing and Xuan points,but also provide new ways and strategies for the diagnosis and treatment of related diseases.

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