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Discussion on clinical pattern differentiation and treatment of Xiaoke disease in Synopsis of the Golden Chamber
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DOI   10.11656/j.issn.1673-9043.2026.01.02
Key Words   Synopsis of the Golden Chamber;Xiaoke disease;pathomechanism;Shenqi Pill
Author NameAffiliationE-mail
ZHANG Xinyi School of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China  
HAO Zheng School of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
Tianjin Key Laboratory of Modern Chinese Medicine Theory Innovation and Transformation, Tianjin 301617, China
GUO Aichun Institute of Medical History and Literature, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China 
1060256010@qq.com 
Abstract
    Based on the theory of zang-fu organs and meridians in Synopsis of the Golden Chamber,the article begins with the original text of the first and second clauses in the chapter on Xiaoke disease(wasting-thirst disease) to delve into its pathomechanism. It summarizes that the etiology of Xiaoke disease lies in the agitation of wind and fire in the Jueyin,with the deficiency of nutrient(ying) and defense(weiqi due to consumptive disease as its pathological basis. The core pathomechanism involves the struggle between hardness and rapidity,deficiency of kidney qi,and inhibited qi transformation. It emphasizes Shenqi Pill(Kidney Qi Pills) as the main formula for treating Xiaoke disease,with the core therapeutic strategy being the restoration of the kidney’s qi-transformation function. Later generations expanded the theory of Xiaoke disease on the basis of Synopsis of the Golden Chamber,including developments in syndromes,etiology,formulas and medicinals,as well as preventive and health-preserving methods. The article highlights the value of Synopsis of the Golden Chamber regarding Xiaoke disease,which holds significant clinical importance for the modern treatment of diabetes.

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