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| Research progress on the mechanism of Shouhui Tongbian Capsule in treating constipation |
| Hits 269 Download times 32 Received:November 22, 2025 |
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| DOI
10.11656/j.issn.1673-9043.2026.02.14 |
| Key Words
Shouhui Tongbian Capsule;constipation;mechanism of action;research progress |
| Author Name | Affiliation | E-mail | | XU Qianqian | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Lin | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Mingfei | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Yuhao | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XIAO Xuefeng | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | kal1219@163.com | | WANG Yuefei | Institute of Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | wangyf0622@tjutcm.edu.cn |
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| Abstract
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| Constipation is a gastrointestinal disease caused by a variety of factors，often leading to anal fissure， hemorrhoids and other complications，which seriously affects the quality of life of patients. At present，the chemical treatment of constipation has problems such as large adverse reactions and drug resistance，while traditional Chinese medicine（TCM）has rich clinical experience in treating constipation，and has become a hot spot for research because of its fewer adverse reactions and better drug compliance. Shouhui Tongbian Capsule is a clinical formula of Professor ZHOU Zhongying of Nanjing University of Chinese Medicine，which is composed of eight Chinese medicines，with the effects of nourishing yin，benefiting qi，eliminating turbidity，and promoting defecation， and is suitable for constipation caused by qi and yin deficiencies. Studies have shown that Shouhui Tongbian Capsule works by repairing the intestinal barrier and regulating constipation-related signaling pathways to treat constipation. In this paper，the mechanism of Shouhui Tongbian Capsule in treating constipation is systematically analyzed and described，aiming to provide a theoretical basis and reference for its further research and development as well as its rational clinical application. |
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