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| Research progress on chemical constituents and pharmacological effects of Mailuoshutong preparation |
| Hits 163 Download times 20 Received:October 20, 2025 |
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| DOI
10.11656/j.issn.1673-9043.2026.03.13 |
| Key Words
Mailuoshutong preparation;chemical constituents;pharmacological effects;superficial thrombophlebitis;deep venous thrombosis |
| Author Name | Affiliation | E-mail | | LIU Yuhao | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | ZHANG Lin | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | LIU Mingfei | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XU Qianqian | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | | | XIAO Xuefeng | School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | kal1219@163.com | | WANG Yuefei | Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China | wangyf0622@tjutcm.edu.cn |
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| Abstract
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| Mailuoshutong（MLST） preparation is composed of twelve traditional Chinese medicinal materials，and it possesses the efficacy of clearing heat and toxins，resolving blood stasis and dredging collaterals，as well as removing dampness and relieving swelling. Research has identified 249 chemical constituents in MLST preparation，including 79 flavonoids，62 terpenoids，38 phenolic acids，22 alkaloids，12 coumarins，11 carboxylic acids，9 esters，5 amino acids，3 phthalides，2 ketones，2 quinones，2 stilbenes，1 aldehyde，and 1 saccharide. It demonstrates a range of pharmacological activities，such as those against superficial thrombophlebitis，deep venous thrombosis，thromboangiitis obliterans，atherosclerosis，and cerebral ischemia-reperfusion injury. This review systematically summarizes the chemical constituents and pharmacological effects of MLST preparation，aiming to provide references for its quality control and further development and utilization. |
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