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An experiment research on the effect of ZhiGan Qing on lipid metabolism in the hypercholesterolaemia model of rabbit
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DOI   10.11656/j.issn.1672-1519.2001.06.21
Key Words   Zhi Gan Qing Chinese drugs;Hypercholes terolaemia;Lipoprotein
Author NameAffiliation
Zhang Jizheng College of Traditional Chinese Medicine of Tianjin 
Fan Yingchang 300193 天津中医学院 
ZhangBoli 300193 天津中医学院 
徐宗佩 300193 天津中医学院 
Abstract
    Objective: To observe the Zhi Gan Qing Chinese drugs in preventing and treatment of hypercholes terolaemia.Method: This experiment established hyperc hole sterolaemia model of rabbit by feeding heavy dosage of cholesterol and observed the changes of lipoprote in metabolism of in blood and liver,it foundout the effect of Zhi Gan Qing Chinese drugs in preventing of hypercholes terolaemia comparing with the Lovastatine.Result: (1)The Chinese drugs markedly lowered total cholesterol(TC), low-density lipoprotein cholesterol(LDL-C),TC/ HDL-Crate(P<0.01 or P<0.05),and markedly low eredactivity of trans-aminaseinserum(P<0.01).(2) The Chinese drugs markedly lowered TC,triglicerid(TG), LDL-Cinliver.Conclusion: The Chinese drugs lowered lipidinserum,promoted metabolism of lipidin liverand protected the function of liver.

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