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Dynamic Research on the Pathogenesis of Apoplexy
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DOI   10.11656/j.issn.1672-1519.2002.02.04
Key Words   Apoplexy pathogenesis;Premonitory symptom;Epidemiology;Biostatistics
Author NameAffiliation
Wang Zhong Chinese Academy of TCM, Beijin 100700 
Zhang Boli 天津中医学院, 300193 
Shen Chundi 江苏省常州市中医院, 213003 
Abstract
    Objective: To explore the biostatistic method for explaining the implicated informations of some symptoms occurred before apoplexy in order to further understand their rule of pathogenesis evolution. Methods: A 1:2 case-control study of etiology was carried out in five time points. After getting materials of Cronboch α and split-half reliability for all symptoms variables epidemiologic and biostatistic analysis were done for them. Results: The main pathogenesis was weak and blood stasis about one month before apoplexy and it became deficiency of both qi and yin one week before onset. These pathogenesis factors became more and more exuberant in the following days and transformed into pathogenic fire and wind period 24 h-72 h before this disease. While these pathogenic fire and wind stirred up each other in blood and body and apopleoxy onset occurred soon. Conclusions: Although these symptoms were different and varied with time in the disease course and there was an influence between them,the evolution rule and the changing trace could be recognized.

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