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| Reproduce Rat Model of Dampness-heat Syndrome and Experimental Observation on the Effect of San Ren Tang(Decoction of Three Kinds of Kernels) |
| Hits 2194 Download times 2331 Received:January 24, 2002 |
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| DOI
10.11656/j.issn.1672-1519.2002.02.22 |
| Key Words
Model of dampness-heat syndrome;Rat;San Ren Tang |
| Author Name | Affiliation | | Chen Shuangbai | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | Chang Shufeng | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | Xiao Zhaocen | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 | | 郭义 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193 |
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| Abstract
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| Objective: To reproduce the rat model of Dampness-heat syndrome. Methods: It was made by compound methods with several factors, including endogenous dampness produced by diet disorder and exopathogenic dampness-heat by high air temperature and humidity.Thus, the model was made by using both exopathic and endopathic evil factoros. Results: There were some changes coincided with the characteristics of dampness-heat syndrome in the model rat, such as body temperature, diet and water intake, urine output, body weight,urination and defecation, tongue picture, mental state etc.Pathological changes also occurred in tongue, intestine, liver and spleen. San Ren Tang was effective for treating this disease. Conclusion: The model of dampness-heat syndrome in rat could be reproduced successfully by the method mentioned above. |
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