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Experimental Study of Inhibition Effect of Fei Yi Wan on Proliferation of Cancer Cells in Lung
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DOI   10.11656/j.issn.1672-1519.2002.02.23
Key Words   Fei Yi Wan;Lung cancer cell;Proliferation;Apoptosis
Author NameAffiliation
Dou Zhiying Tianjin University of Traditional Chinese Medicine, Tianjin, 300193 
Jia Yingjie 天津中医学院第一附属医院, 300193 
Tian Fei 天津中医学院第一附属医院, 300193 
Abstract
    Objective: To study the influence of Fei Yi Wan, compound prescription of Chinese medicine, on proliferation and apoptosis of cancer cells. Methods: A model of small nude mice suffered from human small cell carcinoma of lung was used. Using transmitting electro-microscope technique, the apoptosis induced by Fei Yi Wan was observed. Results: Fei Yi Wan could obviously inhibit the proliferation of lung cancer cells. Meanwhile, a marked effect on the induction of the cells apoptosis was observed by microscope with appearance of apoptosis corpuscle. Conclusion: Fei Yi Wan could markedly inhibit the proliferation of lung cancer cell and induce apoptosis but further investigation was still needed for mechanism illustration.

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