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| Clinical and Experimental Investigation of Gouty Granule for Treating Acute Gouty Arthritis |
| Hits 1784 Download times 2103 Received:April 23, 2002 |
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| DOI
10.11656/j.issn.1672-1519.2002.04.08 |
| Key Words
Gout Granule;TCM and Chinese materia medica;acute gouty arthritis |
| Author Name | Affiliation | | Zhang Ming | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | Jin Ruomin | 上海中医药大学 上海200032 | | Li Bin | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 宁炼 | 上海中医药大学 上海200032 | | 周蓉 | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 周敏 | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 顾荻青 | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 徐文彬 | Yueyang Chinese and Western Medicine Integrated Hospital Attaching to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China |
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| Abstract
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| Objective: To investigate clinical and pharmacodynamic effect of Gouty Granule on acute gouty arthritis. Methods: In clinical investigation, 150 patients were randomly divided into colchicine control group (n=50) and gout granule treatment group (n=100) and clinical therapeutic effect was observed after treating. In the experiment, pharmacologic effect of gout granule, as the main index, including analgesia and anti-inflammation action was investigated (not shown here). Results: The total effective rate in treatment group and control group were 95% and 94% respectively without obvious difference between them (P>0.05).The results of animal experiment indicated that gout granule could obviously reduce the number of mice torsion reaction and raise the pain threshold of mice. Compared with NS group, there was an obvious difference (P<0.05). Conclusion: Gout Granule has definite effect on treating acute gouty arthritis with no obvious side effects. |
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