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| Antagonistic Effect of Lizhong Decoction Against Genetic Toxicity of CTX |
| Hits 1599 Download times 1916 Received:March 19, 2002 |
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| DOI
10.11656/j.issn.1672-1519.2002.04.24 |
| Key Words
Lizhong Decoction;resistance;CTX;MN;SCE |
| Author Name | Affiliation | | He Wenbin | Nanjing University of TCM, Nanjing 210029, China | | Wu Haoxi | Nanjing University of TCM, Nanjing 210029, China | | Zhao Fengming | Nanjing University of TCM, Nanjing 210029, China |
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| Abstract
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| Objective: To observe the resistance of Lizhong Decoction against genetic toxicity of CTX (Cyclophosphamide). Methods:Micronucleus (MN) and sister chromatic exchange (SCE) in mice bone marrow cells were used as indexes in this experiment. Simultaneously the mechanism was explored using mice serum SOD as index.Results: Lizhong Decoction could obviously inhibit the high MN rate and SCE due to CTX.Conclusion: Lizhong Decoction has obvious inhibiting effect on genetic toxicity caused by CTX. |
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