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| Observation of Anti-inflammation of Chuandilong’s in Carrageenin-induced in Mouse Metatarsus |
| Hits 1471 Download times 1957 Received:May 20, 2002 |
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| DOI
10.11656/j.issn.1672-1519.2002.05.25 |
| Key Words
Chuandilong;mouse;inflammation;metatarsal swelling |
| Author Name | Affiliation | | Pang Xiaodong | The General Hospital to Tianjin Medical University, Tianjin 300052, China | | Lin Yaogeng | The General Hospital to Tianjin Medical University, Tianjin 300052, China | | Li Baoli | The General Hospital to Tianjin Medical University, Tianjin 300052, China | | 唐方 | The General Hospital to Tianjin Medical University, Tianjin 300052, China |
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| Abstract
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| Objective: To study the anti-inflammatory effect of Chuandilong (dioscorea nipponica) on arthritis. Methods: The model of acute non-infectious inflammation was induced by carrageenin. There were 2 groups: model group and control group (given Nimesulide).Chuandilong with different dosage, once a day, was given to all mice 3 days before the models were made. The thickness of metatarsus was measured before and 2, 4, 6, 8, 24 hours after the models were made. And serum salivary sialic acid was tested 24 hours after that.Results: Chuandilong could improve the swelling at 8, 24 hours obviously (P<0.05), and has no effect on serum sialic acid. Conclusion: Chuandilong has an anti-inflammatory effect on this mode. |
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