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Quantitative Analysis of Huangqi Injection and Danggui Injection on the Epithelial Cells of Gastric Musosa of Gastric Precancerous Lesion
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DOI   10.11656/j.issn.1672-1519.2002.05.32
Key Words   gastric epithelial cell;gastric barrier;gastric precancerous lesion;acupoint injection
Author NameAffiliation
Wang Yinping Guangzhou University of TCM, Guangzhou 510405, China 
Zha Wei 江苏省中医院, 南京, 210029 
Sun Maofeng 南京中医药大学, 南京, 210029 
李任先 Guangzhou University of TCM, Guangzhou 510405, China 
吴旭 台湾长庚纪念医院中医部, 台湾 
Abstract
    Objective: To discuss the influenu of Huangqi(Radix Astragali)Injection and Danggui(Radix Angelicae Sinensis)Injection on the epithelial cells of gastric mucosa in rats.Methods: 70 rats were divided into model group 1,model group 2 treatment 1 group,treatment 2 group and normal group.From 9 to 31 weeks Huangqi Injection were injected on Zusanli in treatment 1 group and 2 seperately.Then the gastric pathological test was done,and the main organelles in gastric epithelial cells was analyzed quantitatively.Results: The lesion of gastric mucosa was more serious in model 2 group than in model 1 group.In gastric mucosa,the mitochondrion was degenerated and the intercellular space was enlarged(P<0.05).Acupoint injection in this experiment could treat gastric precancerours lesion by improving the funcion of gastric epithelial cell,shortening the intercellular space and protecting the gastric barrier(P<0.05).Conclusion: The lesions of gastric epithelical cells are associated with the lesion of gastric barrier and gastric precancer.Acupoint injection can prevent the gastric precancerous lesion effectively by improving the structure and function of epithelial cells and protecting the gastric barrier.

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