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Serial Clinical Report on Preventing and Treating Chronic Renal Failure (CRF)with Integrated Western and Traditional Chinese Medicine and Mechanism Study with Molecular Biology
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DOI   10.11656/j.issn.1672-1519.2002.06.01
Key Words   integrated traditional Chinese and western medicine;chronic renal failure;Baoshen Tablet;molecular biology
Author NameAffiliation
Wang Gang Jiangsu Hospital of TCM, Nanjing 210029, China 
Abstract
    The advantages of treating CRF by western medicine or TCM were proposed respectively on the basis of clinical experiences and it laid the foundation for treating this disease by using both methods together. The serial clinical experiences of preventing and treating CRF in our hospital were summarized. A new method of TCM on preventing and treating CRF at 3-level was introduced, which including not only the clinical summarization and follow-up survey of large samples, but also special diagnosis and treatment experiences and integrated prevention and treatment. The mechanism of Chinese patent medicine Baoshen Tablet may be associated with lowering endothelial oxidation LDL receptors, cellular proliferative factor TGF-β, the mRNA expression of the main ingredient of extra-cellular matrix Ⅰ,Ⅳ collagen in kidney and inhibition of proliferation and apoptosis of mesangial cells.

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