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Influence of Xingbei Chongji on Phospholipase A2 (PLA2) of Guinea Pig with Asthma
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DOI   10.11656/j.issn.1672-1519.2002.06.06
Key Words   bronchial asthma;Xingbei Chongji;Phospholipase A2 (PLA2)
Author NameAffiliation
Sun Zengtao The Second Affiliated Hospital toTianjin University of TCM, Tianjin 300150, China 
Zhang Hong The Second Affiliated Hospital toTianjin University of TCM, Tianjin 300150, China 
Wang Dehui The Second Affiliated Hospital toTianjin University of TCM, Tianjin 300150, China 
魏葆琳 The Second Affiliated Hospital toTianjin University of TCM, Tianjin 300150, China 
Abstract
    Objective: To discuss the influence of Xingbei Chongji on PLA2, the key substance in asthma. Method: The asthma model was induced by ovalbumin provocation.The changes of PLA2 and the inflammatory cells,TXB2, 6-k-PGFα in BALF(bronchi-pulmonary alveoli lavage fluid) were observed. The symptoms of asthma were analyzed simultaneously. Result: PLA2 and TXB2 in treatment group were lowered.Eosinophil in BALF was reduced obviously.The provocative duration and symptoms were improved. Conclusion: Xingbei Chongji plays a role of controlling inflammation and asthma by lowering PLA2.

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