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Influence of Qingre Huazhi Granule on GAS and VIP in mouse with heat due to food stagnation
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DOI   10.11656/j.issn.1672-1519.2003.02.13
Key Words   Qingre Huazhi Granule;food stagnation model;GAS;VIP
Author NameAffiliation
ZHAO Xia Guangzhou University of Traditional Chinese Medicine, Guangzhou 510105, China 
LUO Xing-hong 四川省中医研究院中医研究所, 成都, 610031 
LIU Shu-tang 河北承德中药集团有限责任公司, 承德, 067000 
汪受传 南京中医药大学, 南京, 210029 
Abstract
    [Objective] To explore the influence of Qingre Huazhi Granule(clearing away the heat and removing the food stagnation)on gastrin(GAS)and vasoactive intestinal peptide(VIP)in mouse with heat due to food stagnation. [Method] The content of GAS and VIP in plasma and the tissue of small intestine of each group were detected by radioimmunoassay simultaneously. [Result] In model group the content of GAS was lower in plasma and small intestine tissue and VIP in small intestine tissue increased.After treatment with Qingre Huazhi Granule GAS but VIP,was increased with an obvious dif-ference with that in model group. [Conclusion] The mechanism of Qingre Huazhi Granule treating pediatric food stagnation is associated with modulation of GAS secretion and improvement of gastrointestinal peristalsis.

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