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| Anti-inflammatory effect of Gout Infusion Preparation (GIP) on acute gouty arthritis |
| Hits 1549 Download times 2318 Received:March 02, 2003 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2003.04.14 |
| Key Words
Gout Infusion Preparation (GIP);Traditional Chinese Medicine and Chinese herbs;acute gouty arthritis;animal experiment |
| Author Name | Affiliation | | ZHANG Ming | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | JING Ruo-min | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | WANG Hong-mei | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 李斌 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 宁炼 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 周蓉 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 周敏 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 顾荻青 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China | | 徐文彬 | Yueyang Hospital of Integrated Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China |
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| Abstract
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| [Objective] To investigate the clinical effect of Gout Infusion Preparation (GIP) on acute gouty arthritis and its anti-inflammatory action in experiment. [Methods] One hundred and fifty patients were randomly divided into colchicine control group (n=50) and GIP treatment group(n=100).Clinical effect after treating, including the relieving of joint pain and swelling and its function recovery, was observed. In experiment anti-inflammatory test was mainly investigated. [Result] Results of clinical investigation showed that GIP could release ache and tumefaction of acute gout, and reform the function of joint, without obvious difference with those in the control group (P>0.05). Overall effective rate in treatment group was 95% and in control group was 94%. Result of animal experiment indicated that GIP could inhibit the swelling of ear auricule in mice and joint swelling in rats foot induced by inflammatory-inducing agents and decrease WBC count in the inflammatory exudates of the mice and inhibit ankle joint’s swelling in rats caused by MSUC. There was obvious difference between treatment and control group (NS)(P<0.05). [Conclusion] GIP has undoubted effect on anti-inflammation, analgesia and preventing acute attack of the gouty. |
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