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| Influence of Qiangxin Chongji on neuroendocrine level in rats with congestive heart failure |
| Hits 1588 Download times 2110 Received:March 13, 2003 |
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| DOI
10.11656/j.issn.1672-1519.2003.04.29 |
| Key Words
congestive heart failure (CHF);Qiangxin Chongji;angiotensinⅡ(AⅡ) |
| Author Name | Affiliation | | SUN Lan-jun | The Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | LI Hui-zhen | The Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | ZHAO Ying-qiang | The Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | 王保和 | The Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China |
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| Abstract
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| [Objective] To investigate the influence of Qiangxin Chongji on neuroendocrine level in rats with congestive heart failure (CHF). [Methods] Seventy CHF models were made in wistar rats according to the modified method by constriction of abdominal aorta. Captopril and Shengmaiyin (a patent Chinese medicine) were used as konwn drug. There still were model group and blank group. AngiotensinⅡ(AⅡ) was detected before and after treatment. Qiangxin Chongji could inhibit the activity of renin-angiotensin, improve heart function and thus ammeliorate clinical symptoms in CHF and decrease death rate. [Conclusion] Qiangxin Chongji have influence on neuroendocrine in rats with CHF. |
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