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| Influence of SFPS on [Ca2+]i of SGC-7901 |
| Hits 1735 Download times 1836 Received:March 13, 2003 |
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| DOI
10.11656/j.issn.1672-1519.2003.04.33 |
| Key Words
SFPS;SGC-7901;[Ca2+]i;action of effect |
| Author Name | Affiliation | | GAO Shi-yong | Postdoctoral Programme, Institute of Material Medica of Harbin University of Commerce, Harbin 150076, China | | JI Yu-bin | Postdoctoral Programme, Institute of Material Medica of Harbin University of Commerce, Harbin 150076, China |
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| Abstract
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| [Objective] To study the change of Ca2+ in SGC-7901, for exploring the mechanism of apoptosis induced by SPFS. [Methods] Intracellulari [Ca2+]i was measured with laser confocal microscopy using Fluo-a/Amoribe labeling technique. [Result] SFPS, increased [Ca2+]i first and then declined. After giving CaCl2, i rise again. [Conclusion] SFPS can induce apoptosis of cancer cells through enhancing [Ca2+]i in SGC-7091. This kind of rises of Ca2+ is from the release of cellular storage. |
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