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| Effect of Tablet Biejiaruangan Compositae on the Proliferation of Myofibroblasts |
| Hits 1621 Download times 1803 Received:July 10, 2003 |
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| DOI
10.11656/j.issn.1672-1519.2003.05.29 |
| Key Words
Tablet Biejiaruangan Compositae;heart;fibroblasts;cell proliferation;cell circle |
| Author Name | Affiliation | | LI Shao-sheng | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China | | LI Lan_sun | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China | | GUO Wen-yi | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China | | 张荣庆 | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China | | 布伦 | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China | | 李俊峡 | Xijing Hospital of the Forth Military Medical University, Xi’an 710032, China |
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| Abstract
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| [Objective] To study the effects of Tablet Biejiaruangan Compositae on the proliferation of myofibroblasts.[Methods] Cardiac fibroblasts (CFs) were cultured from neonatal rat hearts. Proliferation of the cells was determined by MTT test.The cell circle was measured by flowcytometry analysis.[Results] Tablet Biejiaruangan Compositae attenuated the proliferation of myofibroblasts obviously, and arrested CFs cell progression at G1 phase.[Conclusion] Tablet Biejiaruangan Compositae can prevent and cure cardiac fibrosis. |
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