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| Experimental research about the influence of Huangqi Injection on hemodynamics in rats with acute heart failure |
| Hits 2055 Download times 2108 Received:December 01, 2003 |
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| DOI
10.11656/j.issn.1672-1519.2003.06.27 |
| Key Words
Huangqi Injection;acute heart failure;hemodynamics;experimental research |
| Author Name | Affiliation | | LI Shu-rui | Hebei Handan Center Hospital, Handan 056001, China | | HAO Jian-feng | Hebei Handan Center Hospital, Handan 056001, China | | WANG Yi | 天津中医学院, 天津, 300193 | | 高秀梅 | 天津中医学院, 天津, 300193 | | 胡利民 | 天津中医学院, 天津, 300193 |
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| Abstract
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| [Objective] To investigate the influence of Huangqi Injection in different dosages in rats with acute heart failure (AHF).[Methods] The AHF models were reproduced in rats by pentobarbital sodium. The changes of hemodynamics were observed in rats with acute heart failure treated with Huangqi Injection in different dosages.[Results] Large and middle dosage of Huangqi Injection can obviously enhance cardiac contractility, increase heart rate and rise blood pressure (P<0.05~0.01) with no significant influence on above-mentioned indexes of hemodynamics in rats with acute heart failure in Huangqi Injection group of small dosage (P>0.05).[Conclusion] Large and middle dosage of Huangqi Injectioin had effect against heart failure. |
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