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Study for mutagenic of Synthetic borneol |
Hits 1479 Download times 1930 Received:May 30, 2003 |
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DOI
10.11656/j.issn.1672-1519.2003.06.30 |
Key Words
synthetic borneol;ames test;mutagenicity |
Author Name | Affiliation | LIU Yang | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | LI Yi-lan | 天津市卫生防病中心, 天津, 300100 | HU Li-min | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | 范祥 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | 周蕾 | 天津市卫生防病中心, 天津, 300100 | 张伯礼 | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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Abstract
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[Objective] To observe the mutagenicity effect of Synthetic Borneol.[Methods] Ames test was used.[Results] The number of backward mutant colony of four bacterial strains induced by Synthetic Borneol at the concentration within 0.4~250 μg/plate was quantified. The results did not display a significant increase compared with that induced by dimethylsulfoxide, whether with metabolic activation system (S9-mix) or not. Moreover, the backward mutant colony had normal background.[Conclusion] Synthetic Borneol did not possess evident mutagenicity through our study. |
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