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Study for mutagenic of Synthetic borneol
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DOI   10.11656/j.issn.1672-1519.2003.06.30
Key Words   synthetic borneol;ames test;mutagenicity
Author NameAffiliation
LIU Yang Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
LI Yi-lan 天津市卫生防病中心, 天津, 300100 
HU Li-min Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
范祥 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
周蕾 天津市卫生防病中心, 天津, 300100 
张伯礼 Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
Abstract
    [Objective] To observe the mutagenicity effect of Synthetic Borneol.[Methods] Ames test was used.[Results] The number of backward mutant colony of four bacterial strains induced by Synthetic Borneol at the concentration within 0.4~250 μg/plate was quantified. The results did not display a significant increase compared with that induced by dimethylsulfoxide, whether with metabolic activation system (S9-mix) or not. Moreover, the backward mutant colony had normal background.[Conclusion] Synthetic Borneol did not possess evident mutagenicity through our study.

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