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Exploration of correlation of syndrome differentiation with pathology in diabetic foot
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DOI   10.11656/j.issn.1672-1519.2004.02.08
Key Words   diabetic foot;amputation syndrone differentiation;clear the heat and remove the toxin
Author NameAffiliation
ZHANG Geng-yang The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
FAN Ying-chang 天津中医学院, 天津, 300193 
DU Yu-sheng The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
张学勇 The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
李云平 The First Affiliated Hospital of Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To explore the correlation of syndrome differentiation in TCM with pathologic change of amputated sample in diabetic foot.[Methods] Patients with diabetic foot were divided into stagant deficiency of both qi and blood type,blood stssis in collaterals type,stagnant heat in collaterals type,heat toxin in collaterals type and stagnant deficiency of both qi and yin type according to syndrome differentiation in TCM.Pathologic picture was observed on amputated limbs.[Results] thirteen cases were mainly of stagnant heat in collaterals type,heat toxin in collaterals type and stagnant deficiency of both qi and yin type.The main pathologic changes of amputated artery were manifested as a chronic inflammation in its peripheral vessels or in full thickness in the former.The stagnant heat in collaterals type were mainly as calaification of middle membrane,atrophy,degeration and necriosis of smooth muscle,obvious increase of collagenous fiber.The inflammatory changes were alleviated more obviously than the former.The stagnant deficiency of both qi and yin type were mainly as calcification of middle membrane,decrease of smooth muscle,obvious increase of collagenous fiber.[Conclusion] Syndrome differentiation has certain correlation with pathologic changes of diabetic foot.

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