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Effect of DengZhanHua injection and TongFang dialysis on endotoxin induced IL-1β transcription and interpretation in single nucleus cell |
Hits 1294 Download times 1635 Received:December 23, 2003 |
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DOI
10.11656/j.issn.1672-1519.2004.02.10 |
Key Words
interleukin-1β;Dengzhanhua;Tongfang dialysis membrane;endotoxin |
Author Name | Affiliation | DI Fu-sheng | Tianjin Third Central Hospital, Tianjin 300193, China | YANG Yan | Tianjin Third Central Hospital, Tianjin 300193, China | WEI Su | Tianjin Third Central Hospital, Tianjin 300193, China | 牟富荣 | Tianjin Third Central Hospital, Tianjin 300193, China | 卢奕 | Tianjin Third Central Hospital, Tianjin 300193, China |
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Abstract
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[Objective] To discuss the effect of DengZhanHua injection and TongFang dialysis on endotoxin induced IL-1β transcription and interpretation in single nucleus cell.[Methods] Single nucleus cell,Tongfang dialysis membrane,lipopolysaccharide and Dengzhanhua were cultured together,the IL-1βwas determined by bioassay.[Results] Marked difference was observed when compared with normal group,DengZhanHua could inhibit IL-1β in different degree.The expression of IL-1β could be inhibited in,dialysis therapeutic group and non-dialysis therapeutic group.[Conclusion] Tongfang dialysis membrane, lipopolysaccharide induce the IL-1βtranscription and interpretation. |
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