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Effect of DengZhanHua injection and TongFang dialysis on endotoxin induced IL-1β transcription and interpretation in single nucleus cell
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DOI   10.11656/j.issn.1672-1519.2004.02.10
Key Words   interleukin-1β;Dengzhanhua;Tongfang dialysis membrane;endotoxin
Author NameAffiliation
DI Fu-sheng Tianjin Third Central Hospital, Tianjin 300193, China 
YANG Yan Tianjin Third Central Hospital, Tianjin 300193, China 
WEI Su Tianjin Third Central Hospital, Tianjin 300193, China 
牟富荣 Tianjin Third Central Hospital, Tianjin 300193, China 
卢奕 Tianjin Third Central Hospital, Tianjin 300193, China 
Abstract
    [Objective] To discuss the effect of DengZhanHua injection and TongFang dialysis on endotoxin induced IL-1β transcription and interpretation in single nucleus cell.[Methods] Single nucleus cell,Tongfang dialysis membrane,lipopolysaccharide and Dengzhanhua were cultured together,the IL-1βwas determined by bioassay.[Results] Marked difference was observed when compared with normal group,DengZhanHua could inhibit IL-1β in different degree.The expression of IL-1β could be inhibited in,dialysis therapeutic group and non-dialysis therapeutic group.[Conclusion] Tongfang dialysis membrane, lipopolysaccharide induce the IL-1βtranscription and interpretation.

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