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Expression of MAPK in thyroid cells in rats with Graves’Disease and effect of Chinese
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DOI   10.11656/j.issn.1672-1519.2004.02.30
Key Words   Graves’disease;MAPK;Yiqi Yangyin
Author NameAffiliation
herbal medicine of Yiqi Yangyin WANG Qing-hao Tianjin Medical University, Tianjin 300052, China 
ZHAI Shi-wei Tianjin Medical University, Tianjin 300052, China 
CHEN Ru-quan 湖北中医学院, 武汉, 430061 
Abstract
    [Objective] To investigate the expression of MAPK in thyroid cells of the Graves’disease rats and the effect of Chinese herbal medicine of Yiq Yangyin.[Methods] The GD rats were fed with Yiqi Yangyin decoction and the expression of rat thyroid MAPK was observed by immunohistochemistry.[Results] The expression of MAPK in the Chinese medicine groups was deecreased significantly.[Conclusion] The Chinese herbal medicine plays a role in restraining intracellular information transduction.

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