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Influence of Yi Xin Drink to SOD and MDA activity in mice with viral myocarditis |
Hits 1655 Download times 1719 Received:January 13, 2004 |
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DOI
10.11656/j.issn.1672-1519.2004.03.04 |
Key Words
viral myocarditis;Yi Xin Drink;SOD;MDA |
Author Name | Affiliation | ZHENG Pei-yong | Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai, 300032, China | QIN Zhi-feng | 第二军医大学长征医院, 上海200030 | WEI Xiao | 第二军医大学长征医院, 上海200030 |
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Abstract
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[Objective]To observe the influence of Yi Xin Drink to SOD and MDA activity in mice with viral myocarditis.[Method]One hundred and twenty male Balb/c mice,weighing(20±2)g,were randomly divided into6groups,8 mice in each group were killed after 7d and 14d medication respectively.Serum was prepared from the orbit blood sampling for the SOD and MDA detection.[Result]Comparing with virus control group,the Yi Xin Drink in middle dosage group,big dosage group could increase serum SOD activity at 7d and 14d evidently,decrease the MDA content(P<0.01).[Conclusion]The Yi Xin Drink can alleviate lipid peroxidation damage reaction of myocardial membrane induced by oxy-gen-derived free radidicals. |
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