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| Influence of XNKQ acupuncture therapy on c-fos gene expression of encephalon tissue in rats with cerebral infarction |
| Hits 2158 Download times 2090 Received:March 09, 2004 |
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| DOI
10.11656/j.issn.1672-1519.2004.03.18 |
| Key Words
cerebral infarction;XNKQ acupuncture therapy;c-fos gene;metabolism |
| Author Name | Affiliation | | ZHANG Chun-hong | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China | | WANG Shu | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China | | SHI Xue-min | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China | | 温廷益 | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China | | 刘庆忠 | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China | | 董承超 | The First Affiliated Hospital to Tianjin University of TCM, Tianjin, 300193, China |
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| Abstract
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| [Objective]To reveal the molecule-modulating mechanism of XNKQ acupuncture therapy in cerebral infarction treatment.[Methods]Using Northern hybridization technique,c-fos RNA transcription level of encephalon tissue of rats with focal cerebral infarction and intervention function were observed.[Result]The c-fos gene expression of encephalon tissue of rats with focal cerebral infarction was different,depending on different location and time.In different period of time of cortex,the c-fos gene expression assumed a rise tendency,c-fos RNA gene expression of Hippocampi area assumed downtrend.It was tended to decrease at 1,3,6 h and rise slightly at24,48h in striate body area.XNKQ acupuncture therapy could increase c-fos gene expression peak value of cortex and striate body area in each period of time compared to model group.It could decrease c-fos gene expression peak value of Hippocampi area at1,3h,and increase at6,24,48h.[Conclusion]XNKQ acupuncture therapy can urge nerve cell to produce different suitability change to ischemia damage,and thereby reinforce encephalon tissue rehabilitate capability,and accelerate the reconstruction of neuron network,and recover its common function. |
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