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Effect of early intervention with integrated Chinese and Western Medicine on pulmonary inflammation in SARS
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DOI   10.11656/j.issn.1672-1519.2004.04.02
Key Words   SARS;chest x-ray;TCM integrating with western medicine;pneumonia curative effect
Author NameAffiliation
LIU Bao-yan Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
LI Ping Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
WENG Wei-liang Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
唐旭东 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
方继良 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
黄爱群 北京大学医学部公共卫生学院, 北京, 100083 
梁志伟 广州中医药大学第二附属医院, 广州, 510120 
谢雁鸣 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
胡镜清 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
何丽云 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
汪卫东 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
程谟库 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
佟海滨 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
王融冰 北京市地坛医院, 北京, 100011 
李秀惠 首都医科大学附属佑安医院, 北京, 100054 
黄尧洲 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
张燕萍 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
周卫 Chinese Academy of Tradibional Chinese Medicine, Beinjin100029, China 
李筠 中国人民解放军302医院, 北京, 100039 
任爱民 首都医科大学附属友谊医院, 北京, 100050 
王保国 首都医科大学附属天坛医院, 北京, 100050 
张进萍 北京胸科医院, 北京, 100095 
王凡 北京市中西医结合医院, 北京, 100039 
Abstract
    [Objective] The study provided a scientific evidence for choosing a effective intervention in Severe acute respiratory syndrome(SARS).X-ray chest photograph was used for a main sign to evaluate the effect of TCM(Traditional Chinese medicine)integrating with western medicine in treating SARS.[Methods] 1561chest films of361SARS patients,who came from11hospitals in Beijing,were summarized and analyzed to clarify the effect of TCM integrating with western medicine in treating pneumonia of SARS by multi-center prospective cohort study method.The chest x-rays sum integral(CSI)is introduced to evaluate the inflammation severity of the different areas of the lung,the severe type,the common type and the mild type.All patients were dispersed into two groups,the group of western medicine treating SARS and the group of TCM integrating with western medicine treating SARS.This program was supported by the national Key grant,the clinical research of TCM integrating with western medicine treating SARS.[Results] Generally,in full period of treatment and in all types of lung inflammation,the chest x-rays sum integral in the group of western medicine was5.85±6.5(mean±SD)and 6.67±7.61(mean±SD)in the group of TCM integrating with western medicine,respectively.With the common type in the group of western medicine it was4.79±5.6in the group of TCM integrating with west medicine and was5.40±6.86;with the severe type in the group of western medicine it was7.67±6.34in the group of TCM integrating with western medicine was8.16±7.60.No statistic significance was found between all above two groups(P>0.05).In patients received treatment during the first7days,the chest x-rays sum integral in the group of western medicine was6.39±6.48and in the group of TCM integrating with western medicine was4.40±4.97.It was significant lower in the group of TCM integrating with western medicine than that in the group of west medicine(P=0.0004).With the common type,in the group of western medicine it was4.59±5.22and in the group of TCM integrating with western medicine it was3.99±4.67.No significance was found between these two groups(P=0.12);with the severe type in the group of western medicine it was9.14±7.24and in the group of TCM integrating with western medicine was5.30±5.48,It was significantly lower in the group of TCM integrating with western medicine than that in the group of western medicine(P=0.034).It was indicated that in patiects received treatment during the first7days the absorption of pneumonia in all patients and in the severe type was faster in the group of TCM integrating with western medicine than in the group of western medicine.[Conclusion] In the early period of SARS(in the first7days)TCM integrating with western medicine can accelerate the absorption of pneumonia,and has an apparent predominance than western medicine.

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