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| Effect of Total Saponins in Leaf of Radix Panacis Quinquefolii on Blood Sugar and Serum Insulin in Rats with Alloxan Induced Hyperglycemia |
| Hits 1671 Download times 1832 Received:May 22, 2004 |
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| DOI
10.11656/j.issn.1672-1519.2004.05.06 |
| Key Words
total saponins in the leaf of radix panacis quinquefolli;blood sugar;serum insulin |
| Author Name | Affiliation | | YIN Hui-jun | Beijin Xiyuan Hospital, Beijin 100091, China | | ZHANG Ying | Beijin Xiyuan Hospital, Beijin 100091, China | | JIANG Yue-rong | Beijin Xiyuan Hospital, Beijin 100091, China | | 刘颖 | Beijin Xiyuan Hospital, Beijin 100091, China | | 史大卓 | Beijin Xiyuan Hospital, Beijin 100091, China |
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| Abstract
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| [Objective] the effect of total saponins in the leaf of Radix panacis Quinquefolli on blood sugar and serum insulin in rats with alloxan(tetraoxypyridine)-induced hyperglycemia. [Methods] Rats with hyperglycemia were di-vided randomly into treatment group with high,middle,low dosage of total saponins,Gliclazide group and blank control group.Blood sugar concentration was determined with glucose-oxidase and serum insulin with radioimmunoassay. [Results] The high,middle lower dosage of total saponins and gliclazide could increase the level of serum insulin with per-centage of 29%,28%,22% and 16% respectively. [Conclusion] Total saponins in the leaf of radix panacis Quinquefolli can decrease blood sugar in rats with hyperglycemia and increase serum insulin as well. |
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