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Effect of Acupuncture on Morphology of Microvasculature in Rats with Acute Cerebral Hemorrhage
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DOI   10.11656/j.issn.1672-1519.2004.05.08
Key Words   acupuncture;rats with acute cerebral hemorrhage;microvascular morphology;picture-analysis
Author NameAffiliation
ZHENG Jian-gang The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China 
DU Yuan-hao The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China 
SHI Xue-min The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China 
Abstract
    [Objective] To explore the therapeutic mechanism of acupuncture in treating acute cerebral hemorrhage from the point of view of change of microvasculature. [Methods] The morphologic change of perihematoma microvasculature exhib-ited by cardiac pressure-constant perfusion with the mixture of carbon ink and formaldehyde was observed with optical microscopy and picture-analyzing system. [Results] After cerebral hemorrhage the number of exhibited vessels in perihe-matoma was declined.Most of them is referable to first grade.The total vascular area decreased dramatically.Both the total number of exhibited vessels and the area were increased in control group and had statistical significant difference compared with those in each phase in model group(P<0.05).After acupuncture first grade vessels were interspersed evenly in the perihematoma area with some protruding into the hematoma.The effect was markedly superior to that in control. [Conclusion] The increasing of blood vessels in the hematoma and the peripheral area can supply fibrinolytic substances on the hematoma to accelerate further lysis of it.That may be one of the ways of acupuncture in treating cerebral hemorrhage and facilitating the absorption of hematoma.

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