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Effect of Blool-Replenishing Capsule on tolerance to anoxia |
Hits 1256 Download times 1585 Received:January 13, 2004 |
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DOI
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Key Words
Blood-Replenishing Capsule(BRC);tolerance to hypoxia;mice |
Author Name | Affiliation | WANG Cai-yun | The First Military Medical University, Guangzhou 510515, China | TU Hong-hai | 新疆军区药品仪器检验所, 乌鲁木齐, 830002 | TANG Ai-rong | 第一军医大学南方医院, 广州, 510515 |
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Abstract
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[Objective] To explore the protective effect of Blood-Replenishing Capsule(BRC)on the hypoxic animals and its probable mechanism. [Methods] The effects of Blood-Replenishing Capsule on survival time of mice subjected to normobaric and chemical hypoxia were observed and the oxygen consumption was measured. [Results] Blood-Replenishing Capsule ob-viously prolonged the survival time of hypoxic mice,reduced the oxygen consumption and increased the contents of hemoglobin(Hb)in the bloods.The brain’s SOD was obvious higher and MDA concentration was remarkably lower in BRC groups than those in control groups. [Conclusion] Blood-Replenishing Capsule shows remarkable effect on tolerance to hy-poxia in mice. |
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