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| Influence of Huajian Pills Combined with TCM Syndreme Differentiation on Existence Quality of Tumor Patients in Middle and Late Stage |
| Hits 1614 Download times 1359 Received:August 31, 2004 |
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| DOI
10.11656/j.issn.1672-1519.2005.01.06 |
| Key Words
Huajian pills;TCM syndrome differentiation.;tumor |
| Author Name | Affiliation | | JIA Ying-jie | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China | | SHI Fu-min | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China | | ZHANG Ying | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China | | 贾彦焘 | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China | | 陈军 | The First Affiliated Hospital to Tianjin University of TCM, Tianjin 300193, China |
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| Abstract
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| [Objective] To explore the influence of Huajian(dissipating hard mass) pills combined with Chinese herbs on life quality after chemotherapy in patients with malignancy tumor in middle or late stage,and summarize the clinical therapeutic effect in recent years,standardize the application of Chinese herbs during chemotherapy. [Methods] One hundred and twenty eight cases treated with chemotherapy in our department were randomly divided into chemotherapy only group and TCM integrated with western medicine group. Diameter of tumor body,karnosfky scale,body weight,clinical symptoms,pain,T-cell subtype,NK cell,routine blood test,liver-kidney function were adopted as the main investigated parameters. Statistically, t test was used for measure data,χ2 test for count data,and rank sum test for therapeutic effect. [Results] 1) Changes of tumor body: in integrated group,complete recovery(CR)was found in 6 cases,partial regression(PR) 19 cases,no change(NC) 30 cases,the effective rate was 79.7%,while in chemotherapy only group,CR was in 2 cases,PR 13 cases,NC 26 cases,pregression of disease(PD) 18 cases,the effective rate was 69.5%. 2)Changes of symptoms:in integrated group,improvement rate was 59.42%,rate of stability was 40.58%,while that of chemotherapy group was 33.89%,50.84% respectively. The rate of improvement and stability in integrated group was apparently better than that ofchemotherapy only group,(P<0.05). 3) Changes of pain:52 cases were improved in integrated group,and the improvement rate was 92.10%; in chemotherapy group 37 cases were improved with improvement rate 71.2%. The improvement rate in integrated group was markedly better than that of chemotherapy group,there was no significant difference between these two groups. 4) Activity of CD3,CD4,CD4/CD8 and NK cell were enhanced with different degrees after chemotherapy with significant difference campared with that before treatment(P<0.05, P<0.01),there was significant difference between two groups after treatment(P<0.05). 5)Karnofsky scale and body weight:the improvement rate in integrated group was 56.07%,while in chemotherapy only group was 28.81%,(P<0.05),the improvement rate of body weight increasing in integrated group was 44.9%,while in chemotherapy only group was 32.2%(P<0.05). [Conclusion] Huajian pills is convenient to take,and is a good therapeutic method for tumor patients in middle late stage when combined with clinical TCM syndrome differentiation. |
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